HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 2-Benzyl-3-(2,3-dihydro-benzofuran-5-yl)-2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 3-(1,3-benzodioxol-5-yl)-2,3-dihydro-2-(phenylmethyl)-3a,9a-epoxy-1H-pyrrolo[3,4-b]quinolin-9(4H)-one | HCID 9931480 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Benzyl-3-(2,3-dihydro-benzofuran-5-yl)-2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one | HCID 10318349 | — |
Reaction Steps
The title compound was prepared by stirring 3-(1,3-benzodioxol-5-yl)-2,3-dihydro-2-(phenylmethyl)-3a,9a-epoxy-1H-pyrrolo[3,4-b]quinolin-9-(4H)-one, prepared as in Example 1, with HCl (2 drops of 1N aqueous solution) in a mixture of CH2Cl2 and DMF (4:1) for 72 hours at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06800625B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-a50ca8747ea9476987da629cde4f4ce6 |
| Source note | uspto-grants-2004_10 |