Dichloromethane → HCID 69921427, compound

Participants

Reaction Steps

To prepare compounds 6c, 6d and 6f to a cooled 25 ml round-bottomed flask containing 5c (50 mg, 0.16 mmol), 5d or 5f and Ph3P (51 mg, 0.2 mmol) was added HCA (0.05 ml, 0.3 mmol) in 1 ml CH2Cl2. The reaction mixture was allowed to come to room temperature and stirred overnight. Flash silica gel column chromatography by eluting with hexane to remove the HCA followed by 5% ethyl acetate/hexanes afforded the following compounds:

Provenance & Evidence