反应详情

10 g of dimethylaspartic acid was placed in a 250 ml round-bottom flask, and 40 ml of water was added and stirred for 30 minutes. Then, 7.36 g of concentrated sulfuric acid (concentration: 98%) was slowly added to the flask. After the addition, a reaction was conducted for 2 hours. The reaction solution was concentrated, and azeotroped with 100 ml of toluene to further remove the water. Afterwards, the product was dried under high vacuum, and ground by using a spatula to obtain 15.34 g of N,N-dimethylaspartic acid sulfate as tawny oil (Yield: 95.33%).

1. additionAfter the addition
2. waita reaction was conducted for 2 hours
3. concentrationThe reaction solution was concentrated
4. customazeotroped with 100 ml of toluene
5. customto further remove the water
6. customAfterwards, the product was dried under high vacuum, and ground