HRID392100

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22142380

N~6~-(2-Aminoethyl)-3-nitropyridine-2,6-diamine

C7H11N5O2

结构：CC(C)(C)OC(=O)N1CCc2nc(S(C)(=O)=O)nc(-c3ccc(Cl)cc3Cl)c2C1

HCID69709898

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCc2nc(NCCNc3ccc([N+](=O)[O-])c(N)n3)nc(-c3ccc(Cl)cc3Cl)c2C1

HCID57425229

未命名化合物

PROCEDURE

实验过程

Reaction of tert-butyl 4-(2,4-dichlorophenyl)-2-(methylsulfonyl)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate and 2-amino-3-nitro-6-(2-aminoethylamino)pyridine gave tert-butyl 2-({2-[(6-amino-5-nitro(2-pyridyl))amino]-ethyl}amino)-4-(2,4-dichlorophenyl)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-dedb60e3193e4c64a665a2bf8cc66fbe
来源数据集: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06800632B2
来源说明: uspto-grants-2004_10

反应 SMILES

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:10]2[CH2:22][N:21]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:20][CH2:19][C:11]=2[N:12]=[C:13](S(C)(=O)=O)[N:14]=1.[NH2:30][C:31]1[C:36]([N+:37]([O-:39])=[O:38])=[CH:35][CH:34]=[C:33]([NH:40][CH2:41][CH2:42][NH2:43])[N:32]=1>>[NH2:30][C:31]1[N:32]=[C:33]([NH:40][CH2:41][CH2:42][NH:43][C:13]2[N:14]=[C:9]([C:3]3[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=3[Cl:1])[C:10]3[CH2:22][N:21]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:20][CH2:19][C:11]=3[N:12]=2)[CH:34]=[CH:35][C:36]=1[N+:37]([O-:39])=[O:38]