HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[(2-Aminoethyl)amino]pyridine-3-carbonitrile → Tert-butyl 4-(2,4-dichlorophenyl)-2-({2-[(5-cyano(2-pyridyl))-amino]ethyl}amino)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[(2-Aminoethyl)amino]pyridine-3-carbonitrile | HCID 11369405 | — |
| Reactant | Tert-butyl 4-(2,4-dichlorophenyl)-2-(methylsulfonyl)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate | HCID 69709898 | — |
| Product | Tert-butyl 4-(2,4-dichlorophenyl)-2-({2-[(5-cyano(2-pyridyl))-amino]ethyl}amino)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate | HCID 69761695 | — |
Reaction Steps
Reaction of tert-butyl 4-(2,4-dichlorophenyl)-2-(methylsulfonyl)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate and 2-(2-aminoethylamino)-5-cyanopyridine gave tert-butyl 4-(2,4-dichlorophenyl)-2-({2-[(5-cyano(2-pyridyl))-amino]ethyl}amino)-5,6,7,8-tetrahydropyridino[4,3-d]pyrimidine-6-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06800632B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-3964ee66245449dba0a855bcecd99b1e |
| Source note | uspto-grants-2004_10 |