Ammonium Hydroxide → HCID 69365058, compound

Participants

Reaction Steps

This compound was prepared by the same method as for intermediate 30, using 4-benzofuran-3-yl-butyronitrile (1.05 g, 5.67 mmol), 420 mg of 5% rhodium on alumina, 100 mL of ammonium hydroxide, and 150 mL of ethanol, to afford 770 mg (72%) of the title compound after chromatography: 1H NMR (CDCl3, 400 MHz) δ 7.52 (d, J=8.2 Hz, 1 H), 7.43 (d, J=8.1 Hz, 1 H), 7.38 (s, 1 H), 7.18-7.27 (m, 2 H), 2.72 (t, J=7.0 Hz, 2 H), 2.67 (t, J=7.3 Hz, 2 H), 1.73 (quint, J=7.9 Hz, 2 H).

Provenance & Evidence