HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-2-ol → N-(3-(2-phenylphenoxy)phenyl)pyrid-3-ylmethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-2-ol | HCID 7017 | — |
| Reactant | 3-Bromo-N-(pyridin-3-ylmethyl)aniline | HCID 22663898 | — |
| Product | N-(3-(2-phenylphenoxy)phenyl)pyrid-3-ylmethylamine | HCID 69881268 | — |
Reaction Steps
Using the procedure of Example 342 using N-(3-bromophenyl)pyridin-3-ylmethylamine and 2-phenylphenol (Aldrich) and purifying via preparative HPLC eluting with 90:10 to 80:20 DCM/ethyl acetate gave N-(3-(2-phenylphenoxy)phenyl)pyrid-3-ylmethylamine. Anal Calcd for C24H20N2O.0.2H2O: C, 80.96; H, 5.78; N, 7.87. Found: C, 81.07; H, 5.73; N, 7.63. MS found 353.1 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06800651B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-b7574dc8e00f479ba6c5c2eadaa604d4 |
| Source note | uspto-grants-2004_10 |