Ethanesulfonyl chloride → HCID 22663822, compound

Participants

Reaction Steps

4-Amino-4′-cyanobiphenyl (1.03 g, 5.3 mmol) (TCI) was dissolved in a mixture of 8 ml dichloromethane/2 ml pyridine was treated with ethanesulfonyl chloride (0.61 g, 5.3 mmol) and stirred for 18 h at room temperature. The solution was diluted with dichloromethane and washed twice with 1N HCl. The organic phase was separated, dried over sodium sulfate, filtered, and concentrated in vacuo to afford the title compound. 1H NMR: 7.75 (d,2H,J=8 Hz), 7.67 (d,2H,J=8 Hz), 7.60 (d,2H,J=8 Hz), 7.37 (d,2H,J=8 Hz), 6.90 (s,1H), 3.22 (q,2H,J=8 Hz), 1.45 (t,3H,J=8 Hz).

Provenance & Evidence