7-Methylcoumarin → 7-(Bromomethyl)-2h-chromen-2-one

Beteiligte Stoffe

Reaktionsschritte

7-Methylcoumarin (28 g), 70% benzoylperoxide (1.68 g), and N-bromosuccinimide (30.8 g) was added to 140 mL chloroform in a one liter flask, and the suspension was refluxed overnight. The solution was diluted with 100 mL chloroform. The resulting crude product was recrystallized from 750 mL acetone. A white solid (21 g) with a melting point of 172-176° C. was obtained.

Herkunft & Nachweise