HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → N-Acetyl-D-Galactosamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | N-Acetyl-Hexosamine | HCID 899 | — |
| Reactant | (2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 3037556 | — |
| Product | N-Acetyl-D-Galactosamine | HCID 35717 | — |
| Product | (2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 3037556 | — |
Reaction Steps
N-Acetylhexosamine dialdose may, for example, be manufactured by oxidation of the 6-position of N-acetylhexosamine either chemically or enzymatically. An example of the chemical oxidation is a Fenton method where oxidation is carried out with hydrogen peroxide in the presence of a ferrous salt while that of the enzymatic oxidation is an oxidation using galactose oxidase [EC 1.1.3.9; Cooper, et al.; The Journal of Biological Chemistry, volume 234, pages 445-448 (1959)]. Oxidation of N-acetyl-D-galactosamine with galactose oxidase gives N-acetylgalactosamine dialdose.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06803367B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-206abd35e2754908b10ae8763bb2799f |
| Source note | uspto-grants-2004_10 |