HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 12144703, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 53939994 | HCID 53939994 | — |
| Reactant | HCID 87999076 | HCID 87999076 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 12144703 | HCID 12144703 | — |
Reaction Steps
[2R]-Piperazine-2-carboxylic acid di-(R)-camphor-10-sulfonic acid salt was converted to [2R]-4-t-butoxycarbonyl-1-heptyl-2-hydroxymethylpiperazine by the method of Example 1(b-e). Deprotection of a sample (0.38 g ) with trifluoroacetic acid in dichloromethane, followed by reaction with Example 1(f)(0.36 g) by the method of Example 1(g) gave an oil (0.275 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06803369B1 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-e3e21c1aef0147b6bae636138385efd1 |
| Source note | uspto-grants-2004_10 |