9H-xanthene-9-carbonyl chloride → 9H-Xanthene-9-carboxylic acid (5-methyl-oxazol-2-yl)-amide

HRID 392739Notes

Reaction equation

HRID 392739 reaction equation
[CH3:1][C:2]1[O:6][C:5]([NH2:7])=[N:4][CH:3]=1.[CH:8]1[C:21]2[CH:20]([C:22](Cl)=[O:23])[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[O:13][C:12]=2[CH:11]=[CH:10][CH:9]=1>>[CH3:1][C:2]1[O:6][C:5]([NH:7][C:22]([CH:20]2[C:21]3[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=3[O:13][C:14]3[C:19]2=[CH:18][CH:17]=[CH:16][CH:15]=3)=[O:23])=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 27608929H-xanthene-9-carbonyl chlorideHCID 124951335-Methyl-1,3-oxazol-2-amine

Product 1

HCID 538638689H-Xanthene-9-carboxylic acid (5-methyl-oxazol-2-yl)-amide

Procedure

The title compound, white solid, m.p. 217-220° C. and MS: m/e=306.1 (M+) was prepared in accordance with the general method of example 44a from 5-methyl-oxazol-2-ylamine [Ber. 95, 2419(1962)] and 9-xanthene-carboxylic acid chloride.

Sources & evidence

ORD record
ord-4f453f9bce384f0bacdaaef266d0835f
Source dataset
uspto-grants-2004_10
Patent number
US06803381B1

Reaction notes

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