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HRID392842

反应详情

EQUATION

反应方程式

HRID 392842 的结构方程式

REACTANTS

反应物

3
结构：CCCC[N+](CCCC)(CCCC)CCCC.[O-][I+3]([O-])([O-])[O-]
HCID2724292

未命名化合物

结构：COc1ccc(CO[C@H](CC([SeH])c2ccccc2)[C@@H](O)[C@H](C)C(=O)N2C(=O)OC[C@H]2Cc2ccccc2)cc1
HCID131724612

未命名化合物

结构：COc1ccc(CO[C@H](CC([SeH])c2ccccc2)[C@H](O)[C@@H](C)C(=O)N2C(=O)OC[C@H]2Cc2ccccc2)cc1
HCID131724613

未命名化合物

PRODUCTS

生成物

1
结构：C=C[C@@H](OCc1ccc(OC)cc1)[C@@H](O)[C@H](C)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1
HCID23523020

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

CONDITIONS

反应条件

温度
65 °C

PROCEDURE

实验过程

2.41 g (4.0 mmol, 1.0 eq) of a 7/3 mixture of (4R)-4-benzyl-3-[(2S,3S,4R)-2-methyl-3-hydroxy-4-p-methoxybenzyloxy-6-phenylselenylhexanoyl]-2-oxazolidinone and (4R)-4-benzyl-3-[(2R,3R,4R)-2-methyl-3-hydroxy-4p-methoxybenzyloxy-6-phenylselenylhexanoyl]-2-oxazolidinone are dissolved in 25 mL of chloroform in the presence of 2.45 g (5.6 mmol, 1.4 eq) of tetrabutylammonium periodate. The reaction is stirred at 65° C. for three hours. The chloroform is evaporated off and the residue is then chromatographed on silica gel: eluent (7/3 Cy/EtOAc).

WORKUP

后处理

  1. customThe chloroform is evaporated off
  2. customthe residue is then chromatographed on silica gel