4-(Cyclohexylamino)-3-nitrobenzonitrile → 3-Amino-4-(cyclohexylamino)benzonitrile

Participants

Reaction Steps

A solution of compound 3 (1.23 g, 5.01 mmol) in ethyl acetate (30 mL) and methanol (10 mL) was hydrogenated over 10% palladium on carbon (0.11 g) at 20 psi for 1 h. The reaction mixture was filtered and concentrated on a rotary evaporator to give compound 4 (1.07 g, 99%) as a red-brown solid. ESI-MS m/e 216.3 (M+1).

Provenance & Evidence