Methyl 4-(cyclohexylamino)-3-[[4-(phenylmethoxy)benzoyl]amino]benzoate → HCID 22660776, compound

Participants

Reaction Conditions

Reaction Steps

A solution of compound 47 (0.558 g, 1.11 mmol) in acetic acid (3 mL) was refluxed for 1 h and then stirred at 100° C. for 15 h. The reaction mixture was cooled to rt and concentrated on a rotary evaporator. The residue was coevaporated with toluene (1×) and then purified by column chromatography (silica gel, 8% acetone/toluene (v/v)) to give compound 48 as a white solid (0.234 g, 53%). ESI-MS m/e 441.3 (M+1).

Provenance & Evidence