Diglycolamine → 2-[2-[[7-Chloro-5-[(phenylmethyl)thio]thiazolo[4,5-d]pyrimidin-2-yl]amino]ethoxy]ethanol
Reaction equation
Br[C:2]1[S:3][C:4]2[C:9]([Cl:10])=[N:8][C:7]([S:11][CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:6][C:5]=2[N:19]=1.[NH2:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][OH:26]>>[Cl:10][C:9]1[C:4]2[S:3][C:2]([NH:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][OH:26])=[N:19][C:5]=2[N:6]=[C:7]([S:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:8]=1Participants
3
Procedure
Prepared according to the method of Example 220 using the product of Example 219 (0.3 g) and 2-(2-aminoethoxy)ethanol.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-0387e0295d3c48b7af931250b4857fe6
- Source dataset
- uspto-grants-2004_10
- Patent number
- US06806273B1
Reaction notes
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