HCID 12135181, compound → (7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-piperidin-4-yl-propyl-amine

Participants

Reaction Steps

A solution of (1-benzyl-piperidin-4-yl)-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine (6.86 g, 14.47 mmol) in absolute ethanol (100 mL) was poured onto a slurry of 20% Palladium hydroxide/C (1.4 g) in absolute ethanol (10 mL). The mixture was placed under a hydrogen atmosphere on the Parr shaker at 50 psi for 20 h. The reaction mixture was filtered, and concentrated to give (7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-piperidin-4-yl-propyl-amine (4.2 g).

Provenance & Evidence