HCID 12147050, compound → HCID 9920639, compound

Participants

Reaction Steps

A heterogeneous solution of N-formyl-N-hydroxy-2-(3-benzyloxyphenoxy)ethylamine (300 mg) and Pd/C (100 mg) in methanol (7 mL) was stirred under an H2 balloon for 3 h. The reaction mixture was then filtered through Celite, washing with CH2Cl2. The filtrate was concentrated to a yellow oil which was purified by reverse-phase HPLC to provide N-formyl-N-hydroxy-2-(3-hydroxyphenoxy)ethylamine as a white solid.

Provenance & Evidence