HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[[(2,6-dichlorophenyl)carbonyl]amino]-N-[[1-(3-butenyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester → HCID 53679876, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[[(2,6-dichlorophenyl)carbonyl]amino]-N-[[1-(3-butenyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester | HCID 54502301 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 53679876 | HCID 53679876 | — |
Reaction Steps
A mixture of 4-[[(2,6-dichlorophenyl)carbonyl]amino]-N-[[1-(3-butenyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester (0.19 mmol, 100 mg) and 10% palladium on carbon (200 mg) in EtOH (2 mL) was stirred under a hydrogen atmosphere at room temperature for 15 h. Then, the charcoal was filtered and washed with EtOH (10 mL). The filtrate was removed under vacuum to obtain 37.5 mg (37%) of as a white solid: mp 193-196° C. HR MS: Obs. mass, 519.1818. Calcd. mass, 519.1817 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06806365B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-6ac51f36ae334cfb848d016c25071ca1 |
| Source note | uspto-grants-2004_10 |