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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 393462Generated: October 30, 2026

4-[[(2,6-dichlorophenyl)carbonyl]amino]-N-[[1-(3-butenyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester → HCID 53679876, compound

https://huagongshe.com/reaction/393462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[[(2,6-dichlorophenyl)carbonyl]amino]-N-[[1-(3-butenyl)cyclopentyl]carbonyl]-L-phenylalanine methyl esterHCID 54502301—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 53679876HCID 53679876—

Reaction Steps

A mixture of 4-[[(2,6-dichlorophenyl)carbonyl]amino]-N-[[1-(3-butenyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester (0.19 mmol, 100 mg) and 10% palladium on carbon (200 mg) in EtOH (2 mL) was stirred under a hydrogen atmosphere at room temperature for 15 h. Then, the charcoal was filtered and washed with EtOH (10 mL). The filtrate was removed under vacuum to obtain 37.5 mg (37%) of as a white solid: mp 193-196° C. HR MS: Obs. mass, 519.1818. Calcd. mass, 519.1817 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06806365B2
Source datasetuspto-grants-2004_10
ORD IDord-6ac51f36ae334cfb848d016c25071ca1
Source noteuspto-grants-2004_10