Chloroacetonitrile → HCID 10844811, compound
Reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH2:7][CH2:6]1)=[O:4].Cl[CH2:11][C:12]#[N:13]>>[CH3:1][O:2][C:3]([C:5]1([CH2:11][C:12]#[N:13])[CH2:9][CH2:8][CH2:7][CH2:6]1)=[O:4]Participants
3
Procedure
1-(Cyanomethyl)cyclopentane carboxylic acid methyl ester was prepared from cyclopentane carboxylic acid methyl ester and chloroacetonitrile using the procedure described in example 7 to give a 38% yield. HR MS (C9H13NO2): Obs mass, Calcd mass, 167.0146 (M+).
Workup
- customto give a 38% yield
Sources & evidence
- ORD record
- ord-42ea46baa5044952b7877970ae6eb3bd
- Source dataset
- uspto-grants-2004_10
- Patent number
- US06806365B2
Reaction notes
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