HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenylboronic acid → 4-[5-(4-Trifluoromethyl-phenyl)-benzooxazol-2-YL]-1,4-diaza-bicyclo[3.2.2]nonane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | 4-(5-Bromobenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2]nonane | HCID 22495782 | — |
| Product | 4-[5-(4-Trifluoromethyl-phenyl)-benzooxazol-2-YL]-1,4-diaza-bicyclo[3.2.2]nonane | HCID 22495781 | 54% |
Reaction Steps
The title compound was prepared according to the procedure in Example 44 using 4-trifluoromethyl-phenylboronic acid and 4-(5-bromo-benzooxazol-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane in 54% yield: MS (Cl) m/z 388.4 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809094B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-8174e023984a4d349aae7af05513a28c |
| Source note | uspto-grants-2004_10 |