Ethylamine → N-ethyl-N,N-bis[2-(tert-butoxycarbonylamino)-3-(methoxycarbonyl)propyl]amine
Reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]([CH:15]=O)[CH2:10][C:11]([O:13][CH3:14])=[O:12])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:17]([NH2:19])[CH3:18]>>[CH2:17]([N:19]([CH2:15][CH:9]([NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[CH2:10][C:11]([O:13][CH3:14])=[O:12])[CH2:15][CH:9]([NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:4])[CH3:3])=[O:7])[CH2:10][C:11]([O:13][CH3:14])=[O:12])[CH3:18]Participants
3
Procedure
The product from Example 16A and ethylamine were processed as described in Example 7B to provide the title compound.
Sources & evidence
- ORD record
- ord-1cc49a265b2f4819ad5b63e090784702
- Source dataset
- uspto-grants-2013_09
- Patent number
- US08524753B2
Reaction notes
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