HRID393726

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)[C@@H](CS(=O)(=O)N1CCN(c2ncc(-c3ccc(F)cc3)cn2)CC1)C(=O)O

HCID23519743

未命名化合物

结构：CC(C)[C@@H](CS(=O)(=O)N1CCN(c2ncc(-c3ccc(C#N)cc3)cn2)CC1)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1

HCID23519747

未命名化合物

PRODUCTS

生成物

结构：CC(C)[C@@H](CS(=O)(=O)N1CCN(c2ncc(-c3ccc(C#N)cc3)cn2)CC1)C(=O)O

HCID23519738

未命名化合物

收率 14%

PROCEDURE

实验过程

Prepared according to the method for the preparation of 2-(R)-{4-[5-(4-flurophenyl)pyrimidin-2-yl]piperazine-1-sulfonylmethyl}-3-methylbutyric acid, from 4-(2-{4-[2-(R)-(4-(R)-benzyl-2-oxooxazolidine-3-carbonyl)-3-methylbutane-1-sulfonyl]piperazin-1-yl}pyrimidin-5-yl)benzonitrile (0.70 g), to give the title compound as a white solid (0.70 g, 14%).

WORKUP

后处理

customPrepared