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HRID393727

反应详情

EQUATION

反应方程式

HRID 393727 的结构方程式

REACTANTS

反应物

3
结构：OB(O)c1ccc(Cl)c(Cl)c1
HCID2734330

3,4-Dichlorophenylboronic acid

C6H5BCl2O2

结构：CC(C)(C)OC(=O)N1CCN(c2ncc(Br)cn2)CC1
HCID21914476

tert-Butyl 4-(5-bromopyrimidin-2-yl)piperazine-1-carboxylate

C13H19BrN4O2

结构：CC(C)(C)OC(=O)N1CCN(c2ncc(-c3ccc(F)cc3)cn2)CC1
HCID69850026

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCN(c2ncc(-c3ccc(Cl)c(Cl)c3)cn2)CC1
HCID69894989

未命名化合物

收率 78%

PROCEDURE

实验过程

Prepared according to the method for the preparation of 4-[5-(4-fluorophenyl)pyrimidin-2-yl]piperazine-1-carboxylic acid tert-butyl ester, from 4-(5-bromopyrimidin-2-yl)piperazine-1-carboxylic acid tert-butyl ester (1.00 g) and 3,4-dichlorobenzeneboronic acid (0.61 g), to yield the title compound as a white solid (0.93 g, 78%).

WORKUP

后处理

  1. customPrepared