Phenol → HCID 10286951, compound

Participants

Reaction Steps

Example 38 was synthesized in accordance with the methods of Example 33, except that 4-(3,3-dimethyl-1-butynyl)benzoic acid, 2-(phenylsulfonyl)hydrazide (Example 37) was used instead of 4-phenacetylenyl-benzoic acid, 2-(phenylsulfonyl)hydrazide. MS: 361 (M+1 for C19H24N2O3S1); mp 168-169° C.; TLC (SiO2) Rf=0.7 (50% EtOAc/hexanes); HPLC (phenol hexal column, 1:1CH3CN/H2O+0.1% TFA) 99%, RT=16.8 min. 1H NMR (CDCl3) δ 0.95 (s, 9 H), 1.42-1.50 (m, 2H), 2.56-2.62 (m, 2H), 7.21-7.26 (m, 2H), 7.40-7.60 (m, 6H), 7.94 (d, 2H, J=7.8 Hz), 8.13-8.14 (m, 1H).

Provenance & Evidence