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HRID393888

反应详情

EQUATION

反应方程式

HRID 393888 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)[C@H](CO)NN1CCOCC1
HCID131723652

未命名化合物

结构：C=CCOC(=O)Oc1cccc2[nH]nnc12
HCID178459894

未命名化合物

PRODUCTS

生成物

1
结构：C=CCOC(=O)OC[C@H](NN1CCOCC1)C(=O)OC(C)(C)C
HCID131723651

未命名化合物

PROCEDURE

实验过程

Morpholino-Ser(OAloc) was prepared from Ser(OtBu)-OtBu. Reaction of Ser(OtBu)-OtBu with 4-morpholinecarbonyl chloride in pyridine yielded morpholino-Ser(OtBu)-OtBu. Morpholino-Ser(OtBu)-OtBu was hydrolyzed with TFA to yield morpholino-Ser. Esterification of morpholino-Ser with isobutylene in the presence of a catalytic amount of H2SO4 afforded morpholino-Ser-OtBu. Reaction of morpholino-Ser-OtBu with allyl 1-benzotriazolyl carbonate yielded morpholino-Ser(OAloc)-OtBu. Morpholino-Ser(OAloc)-OtBu was hydrolyzed with TFA in CHCl3 (1:1) to yield morpholino-Ser(OAloc).