Formaldehyde → 2-Ethyl 2-(hydroxymethyl)hexanal

HRID 393974Notes

Reaction equation

[CH2:1]([CH:3]([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2].[CH2:10]=[O:11]>>[CH2:1]([C:3]([CH2:10][OH:11])([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2]

Participants

Reactant 2

HCID 712Formaldehyde

HCID 312412-Ethylhexanal

Product 1

HCID 125384672-Ethyl 2-(hydroxymethyl)hexanal

Procedure

The same also applies to U.S. Pat. No. 5,235,118, which relates to the reaction of 2-ethylhexanal with formaldehyde to give 2-ethyl-2-(hydroxymethyl)hexanal. Here too, formaldehyde is used in substoichiometric amounts relative to the 2-ethylhexanal, and only a small residue of formaldehyde is present in the product solution. The addition of water with subsequent distillation serves for effective removal of unreacted 2-ethylhexanal.

Sources & evidence

ORD record: ord-0435d6ed570c4df98240abd41905d329
Source dataset: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06809224B2

Reaction notes

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