HCID 15383865, compound → HCID 69100859, compound

HRID 394018Notes

Reaction equation

HRID 394018 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([CH2:14][N:15]2[CH2:19][CH2:18][CH2:17][CH:16]2[C:20]([NH2:22])=O)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C([O:30]C(N1C[C@H](O)C[C@H]1C(OC(C)(C)C)=O)=O)C1C=CC=CC=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([CH2:14][NH:15][C:19]([C@H:18]2[CH2:17][CH2:16][CH2:20][NH:22]2)=[O:30])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 15383865HCID 15383865, compoundHCID 86594611HCID 86594611, compound

Product 1

HCID 69100859HCID 69100859, compound

Procedure

The title compound was prepared by methods similar to Steps 1 and 2 of Example 45, using (2R)-N-({(3R)-1-(tert-butoxycarbonyl-3-piperidyl}methyl)pyrrolidine-2-carboxamide and N-benzyloxycarbonyl-O-(tert-butyl)-trans-4-hydroxy-L-proline.

Sources & evidence

ORD record
ord-53582beb658c490587342b62a71c1dcb
Source dataset
uspto-grants-2004_10
Patent number
US06809108B1

Reaction notes

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