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HRID394045

反应详情

EQUATION

反应方程式

HRID 394045 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N1CCC(CN)C1
HCID2756485

tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate

C10H20N2O2

结构：OCC1CCN(Cc2ccccc2)C1
HCID5176654

(1-benzylpyrrolidin-3-yl)methanol

C12H17NO

结构：CC(C)(C)O[C@@H]1C[C@@H](C(=O)N2CCC[C@@H]2C(=O)O)N(C(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)C1
HCID69100730

未命名化合物

PRODUCTS

生成物

1
结构：O=C(NCC1CCNC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1
HCID69101451

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by successively conducting procedures similar to Step 5 of Example 1 and Example 46, using 3-aminomethyl-1-(t-butoxycarbonyl)pyrrolidine [which was synthesized by a method similar to the one described in Japan Kokai Hei 11(1999)-193232, using 3-hydroxymethyl-1-benzylpyrrolidine [taught in Japan Kokai (laid-open) Hei 4(1992)-112868]] and (2R)-1-{(2S,4R)-4-(tert-butoxy)-1-(3,3,3-triphenylpropanoyl)pyrrolidin-2-yl}carbonyl-pyrrolidine-2-carboxylic acid.

WORKUP

后处理

  1. customwas synthesized by a method similar to the one