Sodium 2-mercaptobenzothiazole → 2-methyl-1-phenylpropan-2-yl 2-((4R,6S)-6-((benzo[d]thiazol-2-ylthio)methyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

Participants

Reaction Steps

The procedure was carried out in the same manner as in Example 11, except that 3.5 g of 2-methyl-1-phenylpropan-2-yl 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate was used in place of 30 g thereof, and sodium benzo[d]thiazole-2-thiolate (3.8 g) prepared in Example 10 was used in place of sodium 1-phenyl-1H-tetrazole-5-thiolate. The title compound was obtained (4.6 g).

Provenance & Evidence