HRID394130

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(CN2Cc3c(-c4ccccc4Cl)cc(C=C4CCN(C(C)(C)C)CC4)cc3N(c3c(Cl)cccc3Cl)C2=O)cc1

HCID22647949

未命名化合物

结构：O=C1NCc2c(-c3ccccc3Cl)cc(C3CCC4(CC3)OCCO4)cc2N1c1c(Cl)cccc1Cl

HCID22647951

未命名化合物

PRODUCTS

生成物

HCID22648077

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 7-[(1-tert-butylpiperidin-4-ylidene)methyl]-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one as described in INTERMEDIATE 72. Mass spectrum (ESI): 676.6 (M+1).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-29a99ef0bb714d12b1964b2b703cb097
来源数据集: uspto-grants-2004_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06809199B2
来源说明: uspto-grants-2004_10

反应 SMILES

[C:1]([N:5]1[CH2:10][CH2:9][C:8](=[CH:11][C:12]2[CH:21]=[C:20]3[C:15]([CH2:16][N:17]([CH2:31][C:32]4[CH:37]=[CH:36][C:35]([O:38][CH3:39])=[CH:34][CH:33]=4)[C:18](=[O:30])[N:19]3[C:22]3[C:27]([Cl:28])=[CH:26][CH:25]=[CH:24][C:23]=3[Cl:29])=[C:14]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][C:41]=3[Cl:46])[CH:13]=2)[CH2:7][CH2:6]1)([CH3:4])([CH3:3])[CH3:2].ClC1C=CC=C(Cl)C=1N1C2C(=C(C3C=CC=CC=3Cl)C=C(C3CCC4(OCCO4)CC3)C=2)CNC1=O>>[C:1]([N:5]1[CH2:10][CH2:9][CH:8]([CH2:11][C:12]2[CH:21]=[C:20]3[C:15]([CH2:16][N:17]([CH2:31][C:32]4[CH:33]=[CH:34][C:35]([O:38][CH3:39])=[CH:36][CH:37]=4)[C:18](=[O:30])[N:19]3[C:22]3[C:27]([Cl:28])=[CH:26][CH:25]=[CH:24][C:23]=3[Cl:29])=[C:14]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][C:41]=3[Cl:46])[CH:13]=2)[CH2:7][CH2:6]1)([CH3:4])([CH3:2])[CH3:3]