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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 394152Generated: October 28, 2026

4-Amino-1-Boc-piperidine → Tert-butyl 4-{[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydro-1,6-naphthyridin-7-yl]amino}piperidine-1-carboxylate

https://huagongshe.com/reaction/394152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-1-Boc-piperidineHCID 1268291—
ReactantHCID 22647982HCID 22647982—
ProductTert-butyl 4-{[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2-dihydro-1,6-naphthyridin-7-yl]amino}piperidine-1-carboxylateHCID 22648019—

Reaction Steps

The title compound was prepared from 50 mg of 7-bromo-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-1,6-naphthyridin-2(1H)-one (COMPOUND HHH2) and 63 mg of tert-butyl 4-aminopiperidine-1-carboxylate by a procedure analogous to that described in COMPOUND HHH4. Mass spectrum (ESI) 599 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06809199B2
Source datasetuspto-grants-2004_10
ORD IDord-bf474417958c455b8ee8ae4424a36346
Source noteuspto-grants-2004_10