HuagongsheHuagongshe Chemistry Print Report · For research reference only
Npc164516 → HCID 22648018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Npc164516 | HCID 79038 | — |
| Reactant | 7-amino-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one | HCID 22648015 | — |
| Product | HCID 22648018 | HCID 22648018 | — |
Reaction Steps
The 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-7-[(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)amino]-3,4-dihydroquinazolin-2(1H)-one was prepared from 7-amino-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-3,4-dihydroquinazolin-2(1H)-one (COMPOUND CCC4, STEP A) and 8-methyl-8-azabicyclo[3.2.1]octan-3-one by a procedure analogous to that described in EXAMPLE CCC18, STEP A. Mass spectrum (ESI) 661 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809199B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-bef5c37ed9cf49ce8017b93ce2faad20 |
| Source note | uspto-grants-2004_10 |