HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → (S)-3-{4-[2-(4-chloro-phenyl)-thiazol-4-ylmethoxy]-2-fluoro-phenyl}-2-ethoxy-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | (S)-3-{4-[2-(4-chloro-phenyl)-thiazol-4-ylmethoxy]-2-fluoro-phenyl}-2-ethoxy-propionic acid methyl ester | HCID 68616837 | — |
| Product | (S)-3-{4-[2-(4-chloro-phenyl)-thiazol-4-ylmethoxy]-2-fluoro-phenyl}-2-ethoxy-propionic acid | HCID 10455657 | — |
Reaction Steps
In analogy to the procedure described in example 10 d], (S)-3-{4-[2-(4-chloro-phenyl)-thiazol-4-ylmethoxy]-2-fluoro-phenyl}-2-ethoxy-propionic acid methyl ester was treated with LiOH to obtain (S)-3-{4-[2-(4-chloro-phenyl)-thiazol-4-ylmethoxy]-2-fluoro-phenyl}-2-ethoxy-propionic acid as light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809110B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-d8d69f92ebe9472a93088e2bb2f0ac91 |
| Source note | uspto-grants-2004_10 |