HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 68616855, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 4-(Bromomethyl)-2-(4-chlorophenyl)-5-methyl-1,3-thiazole | HCID 22647586 | — |
| Reactant | [Rac]-2-ethoxy-3-(4-hydroxy-2-methyl-phenyl)-propionic acid ethyl ester | HCID 57792490 | — |
| Product | HCID 68616855 | HCID 68616855 | — |
Reaction Steps
In analogy to the procedure described in example 14 b], [rac]-2-ethoxy-3-(4-hydroxy-2-methyl-phenyl)-propionic acid ethyl ester (example 10 b]) was reacted with 4-bromomethyl-2-(4-chloro-phenyl)-5-methyl-thiazole (JP 62178590 A2) in the presence of cesium carbonate and potassium iodide to yield [rac]-3-{4-[2-(4-chloro-phenyl)-5-methyl-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid ethyl ester as light yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06809110B2 |
| Source dataset | uspto-grants-2004_10 |
| ORD ID | ord-d92412e2b8b94c2c8ae535209c61cf5b |
| Source note | uspto-grants-2004_10 |