Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl heptanoate → 2-[(4-Benzyloxy-2-methyl-phenyl)-hydroxy-methyl]-heptanoic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl heptanoate | HCID 7826 | — |
| 반응물 | Lithium diisopropylamide | HCID 2724682 | — |
| 반응물 | 2-Methyl 4-benzyloxybenzaldehyde | HCID 2759806 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-[(4-Benzyloxy-2-methyl-phenyl)-hydroxy-methyl]-heptanoic acid methyl ester | HCID 68616679 | — |
반응 단계
In analogy to the procedure described in example 125 a], methyl heptanoate was deprotonated with lithium diisopropylamide and reacted with 4-benzyloxy-2-methyl-benzaldehyde in tetrahydrofuran to obtain 2-[(4-benzyloxy-2-methyl-phenyl)-hydroxy-methyl]-heptanoic acid methyl ester as a mixture of two diastereomeric racemates as light yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06809110B2 |
| 출처 데이터셋 | uspto-grants-2004_10 |
| ORD ID | ord-c3eee6e3a1914b60be869ec077ced694 |
| 출처 메모 | uspto-grants-2004_10 |