HuagongsheHuagongshe Chemistry Print Report · For research reference only
Syringaldehyde → HCID 54431732, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Syringaldehyde | HCID 8655 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Piperidin-1-yl-acetic acid | HCID 201097 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 54431732 | HCID 54431732 | — |
Reaction Steps
Monodemethylation of 3,4,5-trimethoxy benzaldehyde using sulphuric acid at 40° C. for 8 hours as described above in Example 1 yields syringaldehyde. Condensation of 3,5-Dimethoxy-4-hydroxy benzaldehyde (syringaldehyde) with ethyl acetoacetate in the presence of piperidine—acetic acid and benzene as the reaction medium at reflux temperature yields the title product. The reaction takes about 3.5 hours for completion.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06602515B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-602d9d1954fa44eb829423fbca755f27 |
| Source note | uspto-grants-2003_08 |