HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N,N-trimethylglycinium → Methyl 3-[4-[(1,1-dimethylethoxy)]-4-oxo-3-[[(phenylmethoxy)-carbonyl]amino]butoxy]-benzenepropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N,N-trimethylglycinium | HCID 248 | — |
| Reactant | Methyl 3-(3-hydroxyphenyl)propionate | HCID 1512675 | — |
| Reactant | AG-H-14083 | HCID 10804815 | — |
| Product | Methyl 3-[4-[(1,1-dimethylethoxy)]-4-oxo-3-[[(phenylmethoxy)-carbonyl]amino]butoxy]-benzenepropanoate | HCID 18176951 | 67.9% |
Reaction Steps
The operation is carried out as in Preparation 1 (Method 2) starting from 270 mg of the phenol prepared in Stage A, 309 mg of 1,1-dimethyl-ethyl N-[(phenylmethoxy)carbonyl]-L-homoserinate and 616 mg of betaine. 320 mg of expected product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06602878B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-cedc6fdd6cc44c19875c49c35baec381 |
| Source note | uspto-grants-2003_08 |