Benzenesulfonyl chloride → HCID 178478902, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to step F of Example 1. Thus, 6-Bromo-1,2,3,4-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-quinolinamine (42 mg, 0.1 mmol) in dimethylformamide (0.2 mL) was treated with triethylamine (0.3 mL, 2.1 mmol), dimethylaminopyridine (10 mg) and benzenesulfonyl chloride (0.014 mL, 0.11 mmol) to afford a solid (17 mg, 32%). MS; (M+H)+=447, 1 Br pattern.

Provenance & Evidence