HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22712342, compound → HCID 22712345, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22712342 | HCID 22712342 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | HCID 22712345 | HCID 22712345 | 90.5% |
Reaction Steps
15 g of N,N-dimethyl-4-bromo-2-methyl-3-nitroaniline is dissolved in about 200 ml of THF and hydrogenated at 20° C. under 5 bars pressure of hydrogen using Raney nickel as catalyst. 12 g of 2-bromo-5-dimethylamino-6-methylaniline is obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06602897B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-aa39f71d8db04dd4a0d2be9cc84c90e8 |
| Source note | uspto-grants-2003_08 |