反应详情

To a solution of 1-(4-fluorophenyl)-5-(2-methyl-5-tetrazolyl)-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (21a), (10.2 g) in dichloromethane (100 mL) was added acrylonitril (7.5 g). The mixture was stirred at room temperature for 16 hours. After evaporation of the solvent, the crude title compound 15a remained as a viscous oil which was used without further purification. Yield 12 g.

1. customAfter evaporation of the solvent
2. customwas used without further purification