HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chlorobenzo[b]thiophene-2-sulfonyl chloride → HCID 70111915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chlorobenzo[b]thiophene-2-sulfonyl chloride | HCID 15158641 | — |
| Reactant | HCID 20680728 | HCID 20680728 | — |
| Product | HCID 70111915 | HCID 70111915 | — |
Reaction Steps
The title compound is prepared as described in EXAMPLE 1, Part K using 6-chloro-benzo[b]thiophene-2-sulfonyl chloride and 3-(S)-amino-1-(furo[3,2-b]pyridin-2-ylmethyl)-pyrrolidin-2-one hydrochloride as starting material. The crude product is purified by column chromatography eluting with a gradient of 25% EtOAc/CH2Cl2 to 90% EtOAc/CH2Cl2 to provide the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06602864B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-6234205d9777455a977a257a6f02fa7b |
| Source note | uspto-grants-2003_08 |