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HRID394610

反应详情

EQUATION

反应方程式

HRID 394610 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1cc2ccc(F)cc2s1
HCID18176323

6-Fluorobenzo[b]thiophene-2-sulfonyl chloride

C8H4ClFO2S2

结构：Cl.N[C@H]1CCN(Cc2cc3ncccc3o2)C1=O
HCID20680728

未命名化合物

PRODUCTS

生成物

1
结构：O=C1[C@@H](NS(=O)(=O)c2cc3ccc(Cl)cc3s2)CCN1Cc1cc2ncccc2o1
HCID70111915

未命名化合物

PROCEDURE

实验过程

The title compound is prepared as described in EXAMPLE 1, Part K using 6-fluoro-benzo[b]thiophene-2-sulfonyl chloride and 3-(S)-amino-1-(furo[3,2-b]pyridin-2-ylmethyl)-pyrrolidin-2-one hydrochloride as starting material. The crude product is purified by column chromatography eluting with 66% EtOAc/CH2Cl2 to provide the title compound as a white solid.

WORKUP

后处理

  1. customThe title compound is prepared
  2. customThe crude product is purified by column chromatography
  3. washeluting with 66% EtOAc/CH2Cl2