Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | HCID 17833025 | HCID 17833025 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 17833026 | HCID 17833026 | 96.5% |
Reaction Steps
Benzyl chloride (0.82 g, 6.5 mmole) was added dropwise to 1.6 g (5.4 mmole) of 3-methyl-2-(α-naphthyl)-6-(4-pyridyl)pyridine and 5 ml of isopropyl alcohol, followed by heating under reflux for 3 hours. After completion of the reaction, 12 ml of ethyl acetate was added. After cooling to 10° C., the mixture was filtered, whereby 2.2 g (yield: 96.5%) of the target product was obtained. By the 1H-NMR, MS, IR and elemental analysis, it was confirmed to be the target product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06603007B1 |
|---|
| Source dataset | uspto-grants-2003_08 |
|---|
| ORD ID | ord-90bc86ae444f43f0b2d3abe233baa8f4 |
|---|
| Source note | uspto-grants-2003_08 |
|---|
