Boron tribromide → HCID 173244476, compound

Participants

Reaction Steps

A starting compound (7)(20.5 mg, 31.9 μmol) was dissolved in 2 mL of chloroform. BBr3 (0.2 mL) was added by using a syringe under a nitrogen atmosphere. After stirred for 3 hours at room temperature, the resultant mixture was diluted by adding chloroform little by little to decompose excessive BBr3. The resultant solution was neutralized with an aqueous solution of sodium bicarbonate and then washed with water. After the solvent was removed, the resultant mixture was dried. As a result, the compound (8) (17.1 mg) was obtained in a yield of 87%.

Provenance & Evidence