反应详情

17.6 g (0.1 mol) of 4-allyloxyacetophenone and 16.6 g (0.1 mol) of 2,4-dimethoxy-benzaldehyde were under an inert dry atmosphere (argon) dissolved in 100 ml of dry ethanol (freshly distilled from sodium under argon atmosphere). The solution was added 1 g of sodium hydroxide and left under stirring for 18 h. The reaction mixture was filtered to give 29.9 g (97%) of 2,4-dimethoxy-4′-prop-2-enyloxychalcone identical to that obtained in Example 2.22, m.p. 74.5-75° C.

1. customan inert dry atmosphere (argon)
2. dissolutiondissolved in 100 ml of dry ethanol (
3. distillationfreshly distilled from sodium under argon atmosphere)
4. additionThe solution was added 1 g of sodium hydroxide
5. waitleft
6. filtrationThe reaction mixture was filtered