反应详情

1.76 g (10 mmol) of 4-allyloxyacetophenone and 1.66 g (10 mmol) of 2,5-dimethoxy-benzaldehyde were under an inert atmosphere (argon) dissolved in 10 ml of dry freshly distilled ethanol, and 100 mg of sodium hydroxide was added to the solution. The mixture was left under stirring for 2.5 h and filtered. The precipitate was recrystallized from methanol to give 2.50 g (83%) of 2,5-dimethoxy-4′-prop-2-enyloxychalcone, m.p. 86-87° C.

1. dissolutiondissolved in 10 ml
2. dry with materialof dry freshly distilled ethanol, and 100 mg of sodium hydroxide
3. additionwas added to the solution
4. waitThe mixture was left
5. filtrationfiltered
6. customThe precipitate was recrystallized from methanol