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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 39506Generated: October 25, 2026

2-Chloro-4-iodoaniline → 3-[(2-Chloro-4-iodophenyl)amino]isonicotinic acid

https://huagongshe.com/reaction/39506

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-iodoanilineHCID 282930—
Reactant2-Fluoroisonicotinic acidHCID 345360—
Product3-[(2-Chloro-4-iodophenyl)amino]isonicotinic acidHCID 57649651—

Reaction Steps

Synthesized as intermediate 1 by reacting 15.7 mmol of 2-chloro-4-iodoaniline with 23.55 mmol 2-fluoroisonicotinic acid. LC/MS [(5.9 min; 376 (M+1)].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524911B2
Source datasetuspto-grants-2013_09
ORD IDord-831f693a9c4b4cb1b2a7ca46a2896ab2
Source noteuspto-grants-2013_09