HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 22568978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl{4-[4-(1-benzyloxycyclopropyl)-3-methyl-phenylethynyl]-phenyl}-acetate | HCID 86585924 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22568978 | HCID 22568978 | — |
Reaction Steps
Using General Procedure E; [4-(1-isopropoxycyclopropyl)-3-methyl-phenylethynyl]-trimethylsilane (Intermediate 80, 250.0 mg, 0.87 mmol) in methanol (10 mL) was treated with potassium carbonate (100.0 mg, 0.72 mmol) and stirred overnight at ambient temperature. The crude alkyne (180 mg, 98%) was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06603019B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-76c0629dbe244193bd2ef75fe7f35a80 |
| Source note | uspto-grants-2003_08 |