Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 6-Chloro-3-nitropyridin-2-ylamine | HCID 2724035 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10727824 | HCID 10727824 | — |
Reaction Steps
Morpholine (4 eq) was added to a suspension of 6-chloro-3-nitropyridin-2-amine (1 eq) in CH3CN, and the reaction mixture was stirred at 70° C. for 5 hours. The solvent was evaporated under reduced pressure, and the residue was triturated with ether to afford the desired compound as a bright yellow powder. LC/MS m/z 225.0 (MH+), Rf 1.79 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06605617B2 |
|---|
| Source dataset | uspto-grants-2003_08 |
|---|
| ORD ID | ord-f81dd760cb274bf8b51c1b59ca147c72 |
|---|
| Source note | uspto-grants-2003_08 |
|---|
